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In addition to organizing DNA, histones play important roles in a number of other cellular processes critical for survival and development.
AK helped in organizing DNA samples and contributed to the manuscript.
We recently identified a family of bacteriophage tubulins, PhuZ, that play a role in spatially organizing DNA during lytic growth and thereby contribute to efficient phage production (Kraemer et al., 2012).
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That these organized segments are larger than individual nucleosomes argues either (i) for a stereotyped multi-nucleosome structure that might allow an uninterrupted approximately 10-bp periodicity, (ii) for a larger 'mega' nucleosome-like structure that might accommodate several hundred base pairs of DNA, or (iii) for a large non-nucleosomal surface that might organize DNA.
A month before Hurricane Sandy, the United States Justice Department gave $1.25 million to the Police Department and the Innocence Project to go back and organize DNA evidence that might help overturn wrongful convictions.
Research is also being conducted on the use of highly organized DNA lattices to detect biological activity of various molecules.
Bizelesin-targeted AT islands are likely to function as strong matrix attachment regions (MARs), domains that organize DNA loops on the nuclear matrix.
Within the chromosomes, chromatin proteins such as histones compact and organize DNA.
EC organized DNA sample collection and storage.
Together, they organize DNA into chromatin and ensure proper gene regulation.
JALC organized DNA sample preparation and participated in SNP discovery and SNP genotyping.
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CEO of Professional Science Editing for Scientists @ prosciediting.com