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Boundaries between regions with different molecular 'addresses' are considered, in plants as in Drosophila, as organizing centres for lateral organ development.
Elsewhere, the capitals of provinces and other administrative divisions are the main towns, having grown to considerable size as the organizing centres for their territories.
Moreover, our results on heterologous cell fusion between muscular and non-muscular cells demonstrate that the centrosomes of the undifferentiated non-muscle cells do not play a dominant role as microtubule organizing centres in the heterokaryons.
Since centrosome proteins accumulate at the nuclear surface in these differentiating cells [6] [8], we investigated whether nuclei represented the sole microtubule organizing centres and whether the residual "centrosomal elements" (i.e. centriole-containing clusters as described in [7]) had lost their original potential of microtubule nucleation.
Land plants have evolved dispersed (Wasteneys 2002) or pleiomorphic (Brown and Lemmon 2007) microtubule organizing centres (MTOCs) responsible for nucleating the diverse microtubule arrays associated with cell division and differentiation.
However, hESC hanging-drop protocols appear to require small clumps of cells [33], and we wished to minimize the variability and potential for multiple organizing centres that might arise in this situation.
Similar(53)
The location of the organizing centre, introduced by Balakotaiah and Luss, and some features of the butterfly singularity are discu particularly with reference to variations in the ratio of activation energies.
It is the chief organizing centre of most ecosystem functions, and it is of critical importance in agricultural science and ecology.
The centrosome is the primary microtubule organizing centre of the cell.
Indeed, one study has demonstrated that phosphorylated β-catenin localises to centrosomes and may regulate the microtubule organizing centre [34].
While kinesins transport towards the plus ends of microtubules and therefore the cell periphery, dyneins are adjusted to the minus ends, which locates at the organizing centre of microtubules.
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