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Similar (re)organization was detected in normal males and thus this was not attributed to the effect of NBR.
Retinotopic organization was detected using a polar angle experiment (Sereno et al. 1995; Engel et al. 1997).
In some recordings from the SCN of mice lacking a key intercellular signal, some temporal organization was detected, whereas spatial organization was lacking.
After 20-50 generations, however, a novel TG1-3 organization was detected on the same telomeric sequence, which had a previous rearrangement.
Furthermore, in both studies only one type of 4qter organization was detected, and this was structurally similar to human 4qA up to a point just distal of the Beta satellite array, and included 4q specific subtelomeric sequences.
A very similar sequence organization was detected on PTR chromosome 3p, where D4Z4 and Beta satellite linked arrays were embedded in 4q35-like sequences, spanning from the proximal FRG2C sequence to the distal subtelomeric sequences.
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In fact, responses in chromatin organization were detected in each of the investigated tissues after 24 h at certain (very) low absorbed doses from 211At as previously reported [20].
During this phase both cell shape and microtubule organization were detected using the well-characterized and non-toxic GFP TUB6-expressing line [ 31].
The fact that such hierarchical organization is detected from the transcriptome data implies that at least a subset of the higher-order metabolic network may be regulated at the transcript level.
The same technical approach was followed in the wheat-rye addition lines wheat+6R6R and wheat+7R7R (rye chromosomes 6 and 7 do not contain rRNA genes), and no modification in wheat-origin ribosomal chromatin organization and topology was detected, with similar results to those observed in the euploid wheat (data not shown).
Consistent with this organization, expression of CCL21 was detected within the T zone and CXCL13 was expressed within the follicular areas.
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Justyna Jupowicz-Kozak
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