Sentence examples for organization of expression from inspiring English sources

The information contained in this matrix determines a network's capacity of finely controlling the spatio-temporal organization of expression domains along the strip of nuclei modeled (patterning capabilities).

Despite the mounting research on Arabidopsis transcriptome and the powerful tools to explore biology of this model plant, the organization of expression of Arabidopsis genome is only partially understood.

Using a novel approach to microarray analysis, we show that variability in the large-scale organization of gene expression levels, rather than differences in the expression levels of specific genes, is associated with individual differences in behavior.

Our results contrast with the traditional belief that epigenetic effects on gene expression occur only at the level of specific genes and suggest instead that the large-scale organization of gene expression levels provides important insights into the relationship of gene expression with behavioral variability.

To examine epigenetic influences on the large-scale organization of gene expression levels, we studied the relationship of gene expression organization in the hippocampus with stable individual differences in activity in the open field in genetically identical mice.

We found in multiple microarray experiments that differences in the large-scale organization of gene expression levels in the hippocampus, rather than specific differences in gene expression levels, were associated with individual variability in hippocampus-related behaviors.

A previous study of the large-scale organization of gene expression levels identified power-law like behavior as a universal feature of gene expression levels as measured by microarrays or serial analysis of gene expression (SAGE) [8].

This emphasizes the importance of hybridizing all samples together when microarrays are used to look for biological differences in the large-scale organization of gene expression levels.

We hope that the recognition of this global level of gene expression organization will encourage future studies to understand the potential functional relevance of the large-scale organization of gene expression levels to brain development, pathology, and treatment.

The same association of the variance of gene expression levels with behavioral variability is found with levels of gene expression in the hippocampus of genetically heterogeneous outbred populations of mice, suggesting that variation in the large-scale organization of gene expression levels may also be relevant to phenotypic differences in outbred populations such as humans.

Our experiments suggest substantial variability in the large-scale organization of gene expression levels within the hippocampus.