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We wondered what properties a three-tissue system of DC would have in comparison to Drosophila at different levels of biological organization (cellular, tissue, and inter-tissue), and chose the beetle Tribolium castaneum as a representative model for our investigations.
The organization of information in DC-THERA poses additional challenges, since research focusing primarily on DC requires a characterization of resources by their cell-type specificity that often transcends the characterization provided by generic tools and information resources.
The absence of WIP had a profound effect on the organization of F-actin within DCs.
Evidence showing the importance of podosome organization in DC function comes from Wasp deficient DCs, which lack podosomes, and display trafficking defects [38] and impaired T cell activation [39].
A recent dismissal of their suit prompted the organization of a march on Washington, DC, set for September 16.
Several authors have shown that NF-κB is required for the development of mTECs and organization of the thymic stroma, and the development and differentiation of DCs [ 38- 43].
Number of DCs.
(C) Close up of DCs.
Depolarization of DCs reduced NLC.
One major division of DCs is conventional DCs (cDCs) and plasmacytoid DCs (pDCs).
The differentiation leads to two major subsets of DCs, conventional DCs (cDCs), and plasmacytoid DCs (pDCs).
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