Sentence examples for organization of binding from inspiring English sources
The organization of binding sites in cis-regulatory elements (CREs) can influence gene expression through a combination of physical mechanisms, ranging from direct interactions between TF molecules to DNA looping and transient chromatin interactions.
Hence, this organization of binding sites might represent a more general feature during development, but not limited to early Drosophila embryogenesis [ 26].
In cases where multiple TF molecules do interact, it is generally unknown how the spatial organization of their binding sites affects DNA binding.
If the CRD in the structure of mouse SIGNR1 is not fully ligated with Ca2+, the conformation in the crystal may not reflect the organization of the binding site under physiological conditions.
Importantly, we found that self-organization of coating thiols can induce the formation of binding pockets in AuNPs.
Specificity arose because the organization of Cre-binding repeats of the preferred substrate matched the programmed arrangement of the subunits in the heterotetrameric synapse.
Our concern being the effect of the spatial organization of receptors on binding at equilibrium, we would like to make sure that we simulated ligand-receptor binding in the diffusion-limited regime, so the observation of an effect of clustering can specifically be related to diffusion and geometrical aspects.
Within the dermis, ECM1 has a role in the structural organization of the dermis, binding to perlecan, matrix metalloproteinase-9, and fibulin.
Mutant plants show an even stronger photosensitivity than chy1chy2lut5, a complete lack of qE, the rapidly reversible component of non-photochemical quenching, and a peculiar organization of the pigment binding complexes into thylakoids.
Similar to Bub3, also Cdc4 and Fbw7 are WD40 β-propeller proteins, but the position and organization of the phosphopeptide binding sites in Cdc4 and Fbw7 and in Bub3 are distinct.
Based exclusively on experimental data, this high resolution dynamic 3D-structure of streptomycin in free solution provides a concrete example of conformational pre-organization for binding.
