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Here we describe the organization, functionality, and capabilities of the ICGC Data Portal.
GO enrichment analysis allows users to explore genes represented by GO terms with automated organization functionality, thereby avoiding the need for manual editing.
The majority of significant genes in the "translation group" with both, transcription and translation efficiency being up-regulated, hints at the importance of polysome organization, functionality and activity in adipocyte differentiation.
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Model-driven development allows IT professionals to specify the system functionality, organization and behavior in a logical or platform-independent manner.
Nevertheless, this adds further scheduling complexity due to the RB pre-organization functionality.
Furthermore, histological organization and functionality of reconstructed tissues must approach those of native organs.
Skeletal muscle is composed of fibrils whose organization defines functionality.
This favored a holistic view on systems organization and functionality, further challenging bioinformatics with data size and the need of integrative efforts [2, 3].
Indeed, these efforts still demand for extensive and suitable studies of genomes, transcriptomes, and metagenome data for proper links with sample organization and functionality, considering single species analyses and community approaches.
However, fundamental differences in genomic organization and functionality of the immune system have been found in teleost lineages.
Under these conditions, the observed changes in cell phenotype, which distinguish resting and angiogenic cells, are likely to be mediated by topology-dependent alterations in cytoskeletal organization and functionality [ 19].
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