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We predict that model organisms will continue to directly contribute to efficient functional analysis of tumor-associated somatic variants.
Genetic and biochemical analyses of PBAF subunits in model organisms will continue to reveal these novel functions and may also identify additional components of the PBAF complex.
Understanding the structure of chloroplasts and the regulation of carbon concentrating mechanisms in these organisms will continue to provide additional challenges for the future.
In a Science Perspective (www.sciencemag.org/content/307/5717/1885.full ), Stanley Fields and Mark Johnston have authored a succinct and specific statement of how model organisms will continue to be important for biomedical research in the coming decades.
Research in model organisms will continue to provide unpredictable insights into biological processes, especially if we stay open minded to the research we fund and we continue to support investigators who take on new endeavors.
Whatever strategies are employed, genetic disruption of lncRNAs in whole organisms will continue to be a vital tool to dissect their functional roles and their degree of influence on development and survival.
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As the number of ESTs grows, the number of unique genes in the organism will continue to be refined.
Sepsis due to multidrug-resistant organisms, however, will continue to impede efforts to increase survival.
We are confident that model organisms, especially mice, will continue to provide original and valuable insights into the biology, disease and therapy of the retina.
The frequent invasion of microorganisms, including viruses, bacteria, fungi, parasites, and other eukaryotic and prokaryotic organisms, has threatened and will continue to threaten the life and health of humans and other vertebrates.
If kept in mind by researchers, this dynamic will guarantee that the most important model organism of the 20th century will continue to be one of the most important model organisms of the 21st century and beyond.
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