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Gilbert's "holy grail" is not so holy after all; he believes that the HGP reveals our place amidst the interconnectedness of all life forms: "The data base of the human genome, coupled with our knowledge of the genetic makeup of model organisms, promises to reveal patterns of genes and to show us how we ourselves are embedded in the sweep of evolution that created our world" (1992, p. 97).
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As Matthew Sullivan writes in his contribution to "Life in Our Phage World," the organisms promise to be "the largest source of genetic diversity on Earth," a reservoir of untapped DNA with possible applications in health care, energy, agriculture, and beyond.
Molecularly-tractable model organisms promise the greatest insight into cognitive function.
The establishment of forward genetics in choanoflagellates has provided the first insights into the genetic underpinnings of development in these evolutionarily relevant organisms and promises to illuminate mechanisms underlying intercellular interactions in the progenitors of animals.
A co-culture system containing multiple strains of the same or different organisms holds promise for conversion of the sugar mixture available in different lignocellulosic feedstock into ethanol.
Here, we discuss the advent of the zebrafish as a powerful vertebrate model organism that promises to positively impact immunologic research.
Removal of the organism also promises to be a daunting task.
Recent efforts have therefore begun to generate genomic and developmental genetic resources for organisms with promise as future model systems in evolutionary developmental biology and ecological genetics (e.g. butterflies: [ 3, 4]; honey bees: reviewed in [ 5]; red flour beetle: [ 6]).
Therefore, new pluripotent cell types that are derived from adult organisms hold great promises for regenerative medicine.
The current explosion of sequencing whole genomes from organisms, including mosquitoes, promises many potentially informative genes beyond those included here.
The serine integrases have recently emerged as powerful new chromosome engineering tools in various organisms and show promise for therapeutic use in human cells.
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