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A constant extraction efficiency was confirmed for the target organisms in this study.
As might be expected, the majority of pathogenic organisms in this study were filamentary species (64 %): predominantly Curvularia, Fusarium, and Aspergillus.
The combinations of pH= 7.3, T⩽35°C and EO⩽0.015 could not obviously affect the growth kinetics of the organisms in this study.
However, between the two TTD and log P% models obtained for both organisms in this study, the TTD models of S. Typhimurium and St. aureus showed better prediction (R2= 0.951 and 0.978, respectively) than the log P% models of them (R2= 0.852 and 0.804, respectively).
The latter trend suggests that the likelihood of proteins being observed and expressed in nature increases when they represent orthologs among multiple organisms (in this study, >5 bacteria).
Some cell locations are not inhabited by any organisms in this study.
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In particular, pathogenic E. coli clinical isolates that cause urinary tract infection were chosen as the test organism in this study.
We used Escherichia coli as a unicellular model organism in this study.
Nevertheless, first-generation cephalosporins were not identified as a unique risk factor for either organism in this study.
S. pombe was used as a model organism in this study because it grows easily and has the genes encoding the QTRT1, QTRTD1, and DUF2419 proteins.
To account for the varying amount of TFs for each organism, each reported property was scaled according to the contribution of each TF (by dividing by the number of TFs per organism in this study).
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