Exact(3)
About one-third of all genes in organisms code for, and the majority of drugs target, membrane proteins.
Several previously reported genes from simpler organisms code for proteins that oscillate in abundance.
RNR is thus essential for cellular life, as evident from the observation that all studied organisms code for at least one RNR (with the exception of a few intracellular pathogens that rely on deoxyribonucleotide salvage from their hosts) [ 6].
Similar(57)
In order to limit the search space of compounds, such database approaches would benefit if information was given in which organisms (coded as taxonomy source) and in which organs or cell types these metabolites were known to exist.
The biological features contain information on organisms, coding sequence regions, genes, variations, combined for both contig and singleton members.
Importantly, both these groups are also enriched in organisms coding for the greatest number of toxin domains in their genomes.
It should be noted that a transition from one LysRS to another most probably occurred through an intermediate evolutionary stage in which organisms coded for both LysRSs [ 15].
It describes gene sequences of Saccharomyces cerevisiae and 10 other organisms coding for MDDs selected from a larger library in search for a kinetically favorable MDD.
In all organisms, coding sequences differ in codon usage, match to tRNA abundances, mRNA stability and initiation sites to regulate rates and fidelity of protein expression (reviewed in Gingold and Pilpel, 2011).
All models were named using their associated KEGG organism code.
The conservation parameter indicates the most distant species (KEGG three letter organism code) from human with a conserved phosphosite.
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