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This result demonstrates that the prismatic structures can maintain their organization in spite of the reduction of the organic matrix around them.
On the other hand, in osteoblast-differentiated cells, BAP specifically mineralizes the pre-secreted organic matrix.
Microscopic examination of the bone tissue reveals the deficient mineralization of the organic matrix.
We have developed methods to isolate and purify the spicules, and characterized the organic matrix of the spicules.
The bivalve shell is made of calcium carbonate embedded in an organic matrix secreted by the mantle.
The charge6, conformation7, supramolecular assembly8, and posttranslational cross-linking9 of specific macromolecules of the organic matrix have key multifunctional roles during the biomineralization process.
This process is based on a highly dynamic environment regulated by an organic matrix that nucleates and directs the hierarchical growth and morphogenesis of mineralized tissue5.
In this way, the organic matrix can be easily modulated to systematically access different disorder order compositions as well as different organizations of ELR spherulites.
DDC-SEM observations confirmed the presence of the nanocrystals (high-density material) and a reduction of the low-density material (organic matrix) (Fig. 6g).
The process is based on a tuneable supramolecular organic matrix that enables the growth of aligned nanocrystals into hierarchical mineralized structures.
These results demonstrate the capacity to program the hierarchical structure and resulting properties of the mineralized material by modulating disorder order levels of the ELR organic matrix.
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CEO of Professional Science Editing for Scientists @ prosciediting.com