Because this upregulation is only taking place in the affected organ, pharmacological tools display a relative selectivity at this site, thereby not affecting other systems or organs.
miRNA tissue expression profile was retrieved from miRWalk common organ target tools http://www.umm.uni-heidelberg.de/apps/zmf/mirwalk/ [ 9].Target prediction of miRNAs was performed by using three algorithms, TargetScan, miRanda and Diana-microT [ 10- 12].
Stem cells have the potential for numerous biomedical applications, including therapeutic cell replacement to repair damaged body organs, as tools for studying genetic defects and testing drugs, and as models for studying cell differentiation and early development.
"We concentrate on real pipe organ sounds and tools that let the organist get as much as possible out of the organ".
An organ is a tool or device ("instrument," in the wider sense) for making something happen ("work," in the engineer's sense), and in today's philistine world there is some comfort in seeing that both "organ" and even "work" have everyday musical meanings (as in "Bach's works for organ").
Culture models of tissues and organs are valuable tools developed by basic research that help investigation of the body functions.
These results suggested that 3-D bioengineered scaffolds of porcine organs may have tremendous potential to produce non-immunogenic transplantable organs as well as beneficial tools for biomedical studies on organ re-engineering and repair.
Microcirculatory and endothelial dysfunction contribute to organ failure, and better tools are needed to assess microcirculatory responses to adjunctive therapies.
But today, thanks to the advent of modern imaging tools, the organ of origin can be documented in most of cases by looking at the epicentre of the mass and the pattern of displacement of adjacent organs [ 6].
SURGEONS once made incisions large enough to get to a gallbladder or other organs by using conventional tools they held in their own hands.
