Sentence examples for organ context from inspiring English sources

While studies of cultured cells have led to new insights into biological control, greater understanding of human pathophysiology requires the development of experimental systems that permit analysis of intercellular communications and tissue-tissue interactions in a more relevant organ context.

Drosophila is an excellent in vivo genetic system for analyzing toxin activities in a multicellular and organ context given the highly conserved nature of many host targets of these virulence factors.

The recent introduction of innovative transgenics that specifically label live cilia in vivo with green fluorescent protein (GFP) promises to open up new opportunities to understand the function of cilia in their normal organ context.

Imaging mammalian cilia in vivo has largely relied on DIC optics to detect motile cilia in a limited number of organ contexts where cilia can be made accessible, for instance in the isolated embryonic node [ 7] or the tracheal surface epithelium [ 8].

This makes it easier to determine how to pass on parameters between the scales, and eases the parameterisation of the cell-models in a whole-organ context.

Parameterising cardiac cell models in a whole-organ context is important for multi-scale modelling and ultimately for clinical use of the models, and requires the ability to control and foresee the whole-organ consequences of variations in cell-level model parameters.

This review presents an overview of functional genomics methodologies in the organ-specific context of studying intrahepatic gene expression.

Two general types of error were identified: (1) causal assertions that used overly general terms because they implicitly assumed an organ-specific context and (2) subsumption relations where a site-specific disorder was asserted to be a subclass of the general disorder.

Even if cancers were not observed in the collected organs, genotype context or longer exposure time could play a major role in their development.

Thus, regulation of IL-8 by ATM could promote a metastatic program that is important in an organ-specific context where oxidative stress and cytokine secretion occur.

For example, the floral organ development stage context with 34 genes has an AUC of 0.51.