Sentence examples for organ cmax from inspiring English sources
As a consequence of these changes, while the target organ Cmax showed very little variation with repeated exposure at a dose of 150 mg/kg bw, at high doses of 300 mg/kg the target organ Cmax varied 8-fold in liver and 18-fold in kidney between one and 30 days exposure.
It is important to note that the characteristic time scale of nanoparticle depletion in each organ is qualitatively similar after Cmax is reached (t1/2 ∼100 hours).
Following repeated exposure for 30 days, the target organ AUC increased only 3 4-fold over this dose range, while Cmax increased less than 2-fold (Anand et al., 2006).
All three conjugates also deposited less DOX into normal organs than did an equivalent dose of free DOX, and the Cmax value of free DOX released by DOX- LNA, PEG-ami-DOX, and PEG-hyd-DOX was 32.5, 9.5, and 4.7 μ g/g, respectively.
The pharmacokinetic profile in plasma and organs was complex; thus a noncompartmental approach was utilized to calculate the area under the curve, cmax, tmax, and drug elimination half-time (t1/2).
PK sampling was performed to determine Cmax, and AUC.
The dotted lines represent hundred times and ten times Cmax.
The main outcome measures were the mean AUC0 12h and Cmax.
Cmax, Tmax, AUC(0−t) were determined.
where Cmax is the maximum value of concentration at the wetland inlet.
