Wild type-looking GCs of FAMALGK plants re-iterate the stomatal developmental pathway, undergo further divisions and exhibit correct orderly expression of stage-specific stomatal regulators and cell cycle genes.
While development of wild-type PGCs follows an orderly expression of Prdm1 (BLIMP1), Stella, Tcfap2c, Nanos3 and Dnd1 (Fig 1A,B), Prdm14-null PGCs showed diminished expression of these genes (Fig 1B; supplementary Fig S1D,E online), as well as of regulators of pluripotency (supplementary Fig S1F).
They're small-size shows from big-size personalities, utterly orderly expressions of affection by people who in their public lives may have seemed better geared toward implosion.
The march, organized by the Popular Committee for the World Cup, appeared to be one of the most creative, orderly expressions of resistance yet.
During viral replication, MCPyV, like other polyomaviruses, displays an orderly gene expression cascade in which the LT gene transcript is expressed first (early gene transcription), followed by the expression of the VP1 gene (late gene transcription; Pastrana et al, 2009; Feng et al, 2011).
Recent developments very much broadened our knowledge and understanding of the mechanisms necessary for orderly gene expression (recent review: [ 43]).
The model is capable of simulating orderly and transient expression of meiotic proteins, without relying on putative repressors to shut down gene expression [ 37].
Ime1 and Ime2 exhibit orderly and transient expression during meiosis.
Taken together, we see an orderly progression of gene expression that follows the progressive commitment of nascent mesoderm, from early expression of Mesp1 to the intermediate expression of Smarcd3, Flk1, and the Mef2cAHF enhancer, and finally the later cardiac lineage-specific expression of Tbx5 and Isl1.
For example, chromosomal "loopings" are pivotal for the orderly process of gene expression, by enabling distal regulatory enhancer or silencer elements to directly interact with proximal promoter and transcription start sites, potentially bypassing hundreds of kilobases of interspersed sequence on the linear genome.
Further, we define the orderly progression of gene expression that parallels the commitment of nascent mesoderm to a cardiovascular fate.
