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The first principal component was used to assist in the ordering of expression levels.
First described by Geman and colleagues in 2004 [ 22], the TSP algorithm evaluates the relative expression of all possible pairs of genes in a microarray probe set, and selects those gene pairs for which the ordering of expression is most likely to reverse from one phenotype to the other.
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This technique is therefore a powerful way of uncovering a wide variety of shapes and respects the time ordering of expressions.
Each of these complexes control distinct checkpoints at G1- and S-phase by regulating the ordered of expression of the cyclins that ultimately drive the progression of the cell cycle.
The unique representative probe was selected by using the highest average rank based on the rank ordered matrix of expression changes between treatments and controls.
This ordered sequence of expression as a function of Notch activity levels fixes an ordered sequence for the threshold values of the regulatory functions in our modeling approach.
Table 2A lists the 6 constitutively expressed genes classified in decreasing order of expression (average fold expression of the two tolerant compared to the two sensitive cultivars).
Moreover, the rank order of magnitude of these increases correlated with the rank order of expression levels of the transgene; in the highest-expressing line, Z116A, muscle weights were increased by 57 81% in females and 87 116% in males compared to wild type mice.
The T24 cells express all 3 muscarinic receptors analysed, yielding the following rank order of expression: M1≥ M2> M3 (Fig. 2A ).
To disambiguate the order of expression, evaluation, the rules of precedence, and associability are also presented along with the powerful notion of operator overloading process.
We also utilize the modular design to show that the order of expression of the three subunits along the polycistronic plasmid does not affect the reconstitution of the yeast Piccolo complex in E. coli.
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