Sentence examples for ordered stepwise from inspiring English sources
Our report provides new insights into development of antifolate-resistant malaria and supports the findings of McCollum et al. (10 ) that the mutations in the dhfr gene do not always occur in a predictable, ordered, stepwise manner.
Construction of a large multi-subunit machine such as the proteasome is expected to require high precision [ 44]. 20S CP biogenesis is an ordered stepwise process requiring five dedicated chaperones that have been described in detail [ 45, 46].
By binding with low specificity to single-stranded RNA, CspA can prevent the formation of unwanted secondary structure and thereby narrow the RNA folding landscape (Jiang and Hou, 1997)—a mechanism of action reminiscent of the ubiquitous protein chaperone DnaK (Hsp70), which cycles on and off nascent polypeptide chains to allow ordered stepwise folding (Hartl et al., 2011).
The data obtained from this optimization process were used to build a second-order stepwise linear regression model [ 37] (Supplementary Methods) to determine the relative importance of the individual drugs.
After verifying normal data distribution (skewness < 1.5) Student's t-test was performed by rank-ordered stepwise testing.
Results of the stepwise multiple ordered logistic regression analysis showed that the number of visits was significantly higher in patients with shorter distance from home to hospital, in those with a more severe burden of overall comorbidity, and in those on pharmacological treatment (Model 1 in Table 2).
Our data suggest that the order of stepwise exclusion, rather than the absolute M value, is a better index of the relative expression stability of individual candidate genes within a gene panel.
To address its limitations, we propose a stepwise process to identify criteria and their weights, and rank ordered interventions.
IGENT supports exhaustive search (IGENT_exhaustive) for lower-order interaction and stepwise search (IGENT_stepwise) for higher-order interaction.
For the limited sample, zeroth-order systems built with hybrid training were found to outperform both first-order systems and stepwise regression models in prediction accuracy, while sensitivity analyses confirmed their robustness.
These pumping rates are used in reverse order as a stepwise (monotonically increasing) pumping strategy.
