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The 12 different possible combinations were presented randomly within each recording session and the color order of targets (six possibilities; e.g. from left to right: red, green, yellow) was changed for each recording session.
The order of targets was as follows: empty, GSH, Ni-NTA, amylose, His-GFP, GST-hHSF1, His-NELF-E, His-UBLCP1, and is illustrated in Fig. S1 in Section I.
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The order of target and non-target trials was random throughout the training session but they were balanced to keep the rat motivated.
Presentation order of target and distractor image was randomized, but equal for a CP participant and his/her two matched controls.
Presentation order of target and distractor stimuli, and rotation angles was randomized in each block, but equal for a CP participant and his/her two matched controls.
Selection of distractor stimuli (8 out of the preselected 16) and the presentation order of target and distractor images was randomized prior to each training block, but exactly the same for a CP participant and his/her two matched controls.
Note that the number of itinerated targets is not always equal to the number of learned targets; further, the order of itineration over the targets is not same as the order of target learning, but depends on each trial of the learning process.
> In addition, we studied the order of target sites of miRNAs in the same predicted candidates (Supplementary File S2).
In the blocked group the order of target types was balanced between participants using a Latin square design.
We also checked the order of target sites of different miRNAs in a predicted candidate as in previous studies (Cai et al., 2010; Ding et al., 2014).
The randomly chosen subset of WGA reads to match the number of PF reads in the genomic sequencing experiment is shown as genomic.matched on the x-axis, and sorted in ascending order of target coverage.
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