Sentence examples for order of regulations from inspiring English sources

Using this representation, we do not need to replicate layers of interactions for each increment in the order of regulations, making it efficient and particularly suitable for representing GRNs, where higher-order regulations is a common phenomenon.

Recall that r is the maximum order of regulation between the target gene and its regulators.

The FPC has overall responsibility for financial regulation in the UK and is part of a new order of regulation designed to keep the banks under closer scrutiny.

These include Standard Pearson correlation technique to measure statistical significance of synchronous co-regulation of genes and order of regulation [ 14].

For the first n columns, the entries marked by 1 correspond to instantaneous regulations whereas for the last n columns non-zero entries denote the order of regulation.

That is, it will take into consideration the d-th order Markov rule, for a gene having a maximum order of regulation d with its parents.

Zou et al. [ 2], while highlighting the existence of both instantaneous and time-delayed interactions among genes while considering the parent-child relationships of a particular order, did not account for the regulatory effects of other parents (having different order of regulation than the current one) on that particular child.

Now, we want to assess the degree of interest in adding gene A as a parent of X with a second order regulatory relationship, that is we want to computee MI X, A|{ B, C}), where superscripts on the parent variables denote the order of regulation it has with the child node.

In this case, we cannot use all the N samples for MI computation, rather we have to use (N −  δ) samples where δ is the maximum order of regulation that the gene under consideration has, with its parent nodes (3 in this example).

The marginal probability for each node of this model thus becomes: (6) P (X [ t ] | X [ t − 1 ], …, X [ t − d ] ) = ∏ i = 1 n P (X i [ t ] | Pa (X i [ t ] ) ) The term Pa(X i [ t]) in the above equation represents the parents of gene X i at time t, which can be in the same time-slice or in one of the d previous time-slices (d is the maximum order of regulation) of gene X i at time t.

This is in violation of the biological reality that parents with various orders of regulation can jointly regulate a child.