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Symbiogenesis was considered a possible solution to one of the perplexities of evolutionary biology: How lower-order cells that lacked a nucleus made the jump to a higher order of cells that possessed a nucleus.
Three parameters (rate of change occurrence, rate of change spreading and acceleration of change-contagion) control the order of cells order in the queue, and ultimately determine the emergence and extent of patches-of-change.
Examples include the zebrafish [1], [47] and Xenopus [48], in which convergent extension has many similarities with the process described above: most importantly, it respects the medio-lateral order of cells [47].
However, place-related drive during eSWR did not exclusively determine the firing order of cells during eSWRs.
In both species, the cells move as a collective from one location to another; in chick embryos, there is a "follow the leader" chain migration in which the spatial order of cells is retained [ 3- 7].
Cranial neural crest cells in chick and zebrafish maintain the same neighbors for extensive periods of time and so the spatial order of cells is largely retained [ 4, 10, 34].
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Hartwell, L. H. & Weinert, T. A. Checkpoints: controls that ensure the order of cell cycle events.
From least to most stiff, the order of cell stiffness was as follows: hASC-iPSC, human embryonic stem cell, fibroblast-iPSC, fibroblasts, and, lastly, as the stiffest cell, hASC.
In conjunction with the abundantly deposited ECM in the periosteal sheets, these findings suggest that the order of cell stiffness may depend on the integration of the stiffness of individual ECM components and the extent of cytoskeletal fiber formation.
The order of cell regions in each image is randomly generated for each labeling by each person.
All arrows during sleep/rest indicate the temporal order of cell activation during sleep/rest.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com