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Explicit relations for second moments of stresses were obtained in (Buryachenko and Rammerstorfer 1998) and utilized second and third order interactions between inclusions.
Investigating higher order interactions between the 18 SNPs and environmental factors using BAMSE showed no significant associations.
As will be shown, our method exploits such complementary relations between paths by considering second order interactions between genes, available in external databases.
However, examining higher order interactions between the variants and environmental factors in the present study applying the software package BAMSE did not show any combinations that significantly contributed to the investigated NAFLD-related phenotypes (data not shown).
To investigate higher order interactions between the 18 SNPs and environmental factors we applied the software package Bayesian Association for Multiple SNP Effects (BAMSE) [24], that model gene-environment interactions while accounting for multiple testing.
All first order interactions between the variables added after the first step were assessed.
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Retention ratio, peak variance and peak capacity observed results are modulated by second-order interactions between channel dimensions.
This, in turn, means four classes of interaction, namely the three first-order interactions between pairs of factors and the second-order interaction involving all three factors.
Terms in Eq. (8) of the form *.* denote second-order interactions between two components and terms of the form *.*.* denote third-order interactions.
Four classes of interaction are involved: three first-order interactions between pairs of factors; and one second-order interaction involving all three factors.
In the current study, the separate effect of individual design variable as well as the second-order interactions between these variables, are investigated.
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