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As we found no linkage disequilibrium between these two markers in the reciprocal cross, the interdependency might be part of a higher order incompatibility that includes a cytoplasmically inherited genetic factor.
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This result, however, does not exclude the possibility of incompatibilities for F1 spore growth rate or higher order incompatibilities for viability.
Sixth, we did not explicitly study high-order incompatibility, but because high-order incompatibility is equivalent to two-locus incompatibility with incomplete penetrance, our results apply to high-order incompatibility.
Second, a high-order incompatibility behaves like a two-locus incompatibility with incomplete penetrance.
Incompatibilities between three or more loci are theoretically expected to be more common than incompatibilities between two loci, because a greater proportion of evolutionary paths to higher-order incompatibilities do not pass through a less fit intermediary (Orr 1995).
We suggest that this LG2 allele has to interact with one from another gene inherited from 'Moonglow', whose position is unknown, in order to produce incompatibility (Supplementary Figure 3).
These studies suggest that on the order of 100 incompatibilities explain isolation between closely related species.
Comparison of hybrid incompatibilities in the younger species pair versus the older species pair allows us to make inferences about the order in which incompatibilities arose.
We examined the plasmids for the presence of replication genes in order to determine their incompatibility group.
Different progeny generated by intracytotype crosses (2 x × 2 x) and intercytotype crosses (2 x × 4 x and 3 x × 2 x) were analysed in order to understand endosperm incompatibility phenomena and gamete origins via the heterozygosity rate transmitted to progeny.
In order to explain this incompatibility, several researchers have claimed that classification of tumours on the basis of HER-2/ neu overexpression or amplification may define a subset of breast cancer in which the net effect of a risk factor could be rather more obvious and its impact on breast cancer development more clear [ 3, 7, 8].
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