Some of these sequences constitute the pathogenesis of diseases like AD. Microglia are the critical convergence point for the many diverse triggers in orchestrating the activity of other immune cells in the brain [6].
Recent studies have now shown that the osteocyte also plays a key role in regulating phosphate metabolism and mineral homeostasis, and orchestrating the activity of the bone-forming osteoblasts and bone-resorbing osteoclasts through autocrine, paracrine and endocrine mechanisms [ 92].
To define suitable targets for corresponding pharmacologic therapies, the delineation of key molecules orchestrating the activity of vascular smooth muscle cells as basis for the reorganization of the vessel wall architecture is indispensable.
With gusto, Mr. Green orchestrated the activities of a widening circle of professional acquaintances.
One company orchestrates the activities of many subcontractors.
A constantly changing environment requires cells to orchestrate the activities of signal transduction pathways with high temporal and spatial precision.
This inherent defense network includes anatomical, physical and chemical barriers, circulating molecules, cells with specific phagocytic or lytic abilities, and soluble mediators that orchestrate the activities of each component and their interactions with the acquired immune system.
The API is used by the user interfaces to orchestrate the activities of the compute nodes and provides the methods to load the data, send the data to the nodes and orchestrate the asynchronous multithreaded connections to the ParallelSAM web services (Supplementary Fig. S1).
This observation is captured in the "regulon" concept to describe the strategy used by the cells to orchestrate the activity of the collection of its biochemical pathways [13].
This direct modulation of GHRH neurons by ghrelin parallels the direct effect of ghrelin on NPY neurons, which orchestrates the activity of the appetite network [2].
