Sentence examples for orchestrating dna from inspiring English sources

One of the proteins orchestrating DNA damage response is ATM (ataxia telangiectasia mutated), which plays a central and multiple role in the cellular stress response by monitoring and maintaining DNA integrity (reviewed by [ 4]).

To orchestrate DNA replication in the context of chromatin is a challenge, both in terms of accessibility to the compact structures and maintenance of chromatin organization.

In response to diverse genotoxic stimuli, p53 instigates transcriptional programs and protein-protein interactions which orchestrate DNA repair, cell-cycle arrest, senescence or apoptosis, as appropriate [13] [15].

In fact, in response to different genotoxic stimuli and depending on the degree of activation, p53 can promote transcriptional programs and protein-protein interactions which orchestrate DNA repair, cell cycle arrest, cellular stress responses, cell cycle regulation and differentiation [ 7], and senescence or apoptosis [ 8].

To orchestrate DNA-replication and -repair processes in the context of chromatin is a challenge, both in terms of accessibility and maintenance of chromatin organization.

The DNA damage response (DDR) orchestrates DNA repair and halts cell cycle.

Ataxia telangiectasia and Rad3-related (ATR) threonine serine kinase is one of the key elements in orchestrating the DNA damage response (DDR).

SOD2, SOD1 and CATA are key antioxidant defense enzymes that alleviate the toxic effects of hydrogen peroxide and superoxide anions/radicals produced as a result of various metabolic processes, while PARP1 and PCNA orchestrate DNA replication and damage repair functions to ensure healthy cell proliferation.

Coordinated gene expression controlled by long-distance enhancers is orchestrated by DNA regulatory sequences involving transcription factors and layers of control mechanisms.

ORChestrating the human DNA replication program.

K63-linked chains have important functions in activating kinases in the NF-κB pathway, orchestrating events during DNA repair or changing the localization of membrane proteins.