The report also suggests that an orchestrated combination of psychotherapy, medication and careful case management followed by continued drug treatment can keep more than 40percentt of elderly people well for at least two years.
Collectively with the p53 knockdown results, it is clear that the DD activated an orchestrated combination of stress-responsive transcription factors to adapt cellular homeostasis to this specific type of insult.
Indeed, the strong transgene silencing effects we saw in our lines can be the result of an orchestrated combination of different transcriptional and posttranscriptional effects, which together contribute to the downregulation of the transgene.
Mr. Wetherell tried to orchestrate a combination with Lycos instead, but when he could not reach an accord with Robert Davis, Lycos's strong-willed chief executive, he backed the Yahoo bid.
Since airways macrophages seldom recognize bacterial components individually, the response to different bacterial PAMPs is usually orchestrated by a combination of different TLRs.
Pituitary embryogensis is orchestrated by a combination of intrinsic and extrinsic signals including basic fibroblast growth factors (bFGF), Wnt, sonic hedgehog, and Notch signals (Scully and Rosenfeld, 2002; Heaney and Melmed, 2004; Zhu et al, 2007).
Each type of EMT is assumed to be orchestrated by different unknown combinations of multiple interacting transcription factors and signaling pathways.
Intriguingly, of the 10 TFBS clusters in Table 4, three were involved in "Nervous System Development" or "Function and Axonal Guidance Signaling" and five in immune response, which may indicate that these processes are orchestrated by a several combinations of transcription factors.
He dismisses his early, highly orchestrated manoeuvres as due to a combination of "incredible self-consciousness" and "incompetence – I didn't know to move on stage, so I rehearsed every part, which is why I looked so wooden".
Veteran striker Robinho, in particular, rose to the challenge of filling Neymar's shoes by darting all over the pitch and orchestrating dangerous passing combinations with the likes of Coutinho, Willian, Dani Alves and Roberto Firmino.
Still, the Fanjuls made that and other acquisitions work, through a wily combination of operational expertise and government price supports orchestrated in Washington.
