Sentence examples for orchestrate the expression from inspiring English sources
The E2 ER complex mediates an array of genomic and non-genomic events that orchestrate the expression of a number of genes involved in the regulation of cell proliferation and differentiation.
Several NAC TFs, such as SECONDARY WALL ASSOCIATED NAC DOMAIN PROTEIN 1 (SND1)/NAC SECONDARY WALL THICKENING PROMOTING FACTOR 3 (NST3), have been shown to orchestrate the expression of a cascade of down-stream TFs (e.g., MYB46 and MYB83), which cooperatively regulate the expression of SCW biosynthesis genes34.
Both factors co-ordinately orchestrate the expression of B cell specific genes and immunoglobulin heavy-chain gene rearrangement [22] [24].
The degree of overlap between profiles of REST and CoREST targets during these OL developmental transitions, particularly the final transition, suggests that highly complex and integrated transcriptional regulatory mechanisms involving REST and CoREST are required to orchestrate the expression of genes involved in OL maturation and maintenance.
MicroRNAs orchestrate the expression of the genome and impact many, if not all, cellular processes.
14 16 PPARγ is also deeply involved in diabetes, given its ability to orchestrate the expression of genes involved in lipid metabolism, adipogenesis and inflammation.
Arntl2 drives metastatic self-sufficiency by orchestrating the expression of a complex pro-metastatic secretome.
Because FoxO3a orchestrates the expression of many genes in order to regulate cellular phenotypes in a variety of environmental states, this gene, a factor involved in melanogenesis regulation, may represent a good target for studying antimelanogenic signaling pathways and for designing pharmacological or antimelanogenic agents that regulate melanin synthesis.
We targeted dCas9-KRAB to the HS2 enhancer, a distal regulatory element that orchestrates the expression of multiple globin genes, and observed highly specific induction of H3K9 trimethylation (H3K9me3) at the enhancer and decreased chromatin accessibility of both the enhancer and its promoter targets.
FoxO1 orchestrates the expression of its target genes primarily translocating into nuclear compartment under several stress stimuli.
The AG transcription factor orchestrates the expression of numerous downstream genes (Gómez-Mena et al., 2005; Ito et al., 2007; Ito et al., 2004).
