Also, complex signaling pathways can be treated as a tightly connected network that orchestrates regulation of a specific functional behavior, rather than as individual, separate mechanisms by focusing on a specific oncogenic molecule or its activating event alone [14].
Orchestrated regulation of enzyme expression in the central region will allow glycan production to be enhanced in specific modules, while avoiding moderately the increased production of other unwanted modules.
For this, we used an approach that detects orchestrated regulation of neighboring enzymes in the metabolic network.
The most important factor that affects normal bone remodelling is the tightly controlled and orchestrated regulation of osteoblasts and osteoclasts.
In contrast, a recent study by Elsharkawy determined a role for HDAC1 in the NF-κB orchestrated regulation of MMP13 expression.
We used Haar Wavelet transforms on optimally arranged grid representations of metabolic pathways as a pattern recognition method to detect orchestrated regulation of neighboring enzymes in the network.
Together, orchestrated regulation of oogenesis executed by insulin and ecdysone hormones reassures that the germline differentiation speed is perfectly attuned to external and internal cues.
They can play either permissive or instructive roles, and it is likely that there is a strictly orchestrated regulation of all of them, where some could be involved at early stages of aging and others could take effect only at later times, leading to the aging of neurogenic areas.
These factors orchestrate transcriptional regulation in tune with neuronal responses.
Molecular networks sense multiple signals from the environment, robustly process appropriate cellular responses and orchestrate the regulation of hundreds of genes and proteins to execute these responses.
Since then, his multidisciplinary approach to research has generated important insights into the principles that orchestrate genome regulation, as well as a number of novel algorithms and technologies for exploring this complex landscape.
