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The present results suggest that DM‐β‐CyD is particularly useful in designing oral preparations of tacrolimus with an enhanced bioavailability and a reduced variability in absorption.
Drug delivery systems to the colon are being actively investigated in order to develop oral preparations of peptides and treat local colonic diseases.
Floating calcium alginate beads, designed to improve drug bioavailability from oral preparations compared with that from many commercially available and modified release products, have been investigated as a possible gastro-retentive dosage form.
189, 43 55] we described a novel approach in design of oral preparations intented for intestinal delivery of enzymes, based on reversible immobilization of the latter onto the polymer matrix.
However, the unavailability of intravenous ibuprofen in certain regions of the world and the availability of inexpensive oral preparations has led to off-label nasogastric administration of oral ibuprofen in preterm infants with PDA.
Occasionally, cholinergic mouthwashes or oral preparations that contain pilocarpine may be helpful.
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When food is delivered to the mouth, oral preparation begins.
Neurogenic dysphagia can result in dysfunction in oral preparation, oral transfer, and pharyngeal motility.
In fact, oral preparation, oral transfer, and the initiation of the swallow may be intertwined, especially with food.
However, it is difficult to ensure that an oral preparation disintegrates specifically in the human colon.
Studies have shown that ramosetron oral preparation has potent inhibitory effects on cisplatin-induced vomiting.
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