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PubMed, Embase and the Wanfang database were searched in Oct 2012 using the strategy of (circulating tumor cell OR circulating tumor cells OR CTC or CTCs OR isolated/circulating/disseminated tumor cells OR ITC) AND (Gastric cancer or Gastric Neoplasms or Stomach Cancer) without time or language restrictions.
The ion detected at m/z 60 was identified as thiocyanic acid, which is also a prominent fragment in some TC or ITC spectra.
In case that f(0) = f, both K d,in and K d,out equal to K d,app which can be measured with more traditional techniques such as SPR or ITC.
The majority of these tumour deposits are likely to be micrometastasis or ITC.
All metastatic deposits identified by IHC were either micrometastasis or ITC.
p<0.05 indicates there is significant difference between DMA or ITC and NMA effects.
Similar(47)
Cells treated with either DMSO (control) or ITCs were collected at 24 h and processed for transmission electron microscopy (TEM).
Cells grown on glass coverslips (#1.5, VWR), pre-coated with poly-L-Lysine (Sigma, #P1399), were treated with vehicle or ITCs in 6-well plates.
We also showed that mature DC infiltrates tended to be few in the cases of micrometastases or macrometastases in non-SLNs compared with the cases of negativity or ITCs, although the difference was not statistically significant.
To make sure that we identified not only micro-metastases or ITCs, which are still under discussion regarding their prognostic value, we defined a copy number >250 CK19 mRNA copies as a positive value (Guller et al, 2012).
Recent studies have demonstrated the high sensitivity, high accuracy and cost effectiveness of this immunohistochemical method using CAM5.2 to detect lymph node micrometastasis or ITCs in various tumours originating from the stomach (Cai et al, 1999), colorectum (Oberg et al, 1998; Yasuda et al, 2002), gall bladder (Yokoyama et al, 1999) or bile duct (Tojima et al, 2003).
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Justyna Jupowicz-Kozak
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