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Good controls are ChIP-Chip experiments with cells lacking the IP epitope (for instance Δ seqA; Fig. 6), mock IPs without antibody (Fig. 5A) or IPs with preimmune serum or IPs from cells growing under conditions that are expected to give no or reduced binding of the respective protein (such as 30° for the heat shock sigma factor σ; Fig. 8C).
So-called induced pluripotent stem cells, or iPS cells, can be made directly from adult skin cells by reprogramming them.
Cells made by Dr. Yamanaka's method are called induced pluripotent stem cells, or iPS cells.
Alternatively, organ tissue created by induced pluripotent stem cells, or iPS cells, in a lab dish may also be used to model human diseases like cancer.
Intellectual properties, or IPs, are now highly profitable for the UK theme park industry, particularly within Merlin, the park's owner, which has bankrolled this latest "dark ride".
"We know now that we need more basic research because the human cells we have at the moment – whether embryonic cells or IPS cells – are not, as some people thought in the past, the same as the true embryonic stem cells that we have from mice".
The research involved so-called induced pluripotent stem cells, or iPS cells, which can be made from skin cells and which appear to have the characteristics of embryonic stem cells.
Stem cells generated by this method, known as induced pluripotent cells, or iPS cells, could then be made to mature into any type of adult cell in the body, a finding with obvious potential for medical benefits.
Unless an app is directly infringing on copyrights or IPs, there's nothing they can do.
In Cell this week, Melton and his colleagues report a complex recipe that can transform either human ES cells or iPS cells directly into functional β cells.
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As yet the immunogenic profile of iPS or iPS-derived cells has not been described.
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