Finally, the study was not able to ascertain what proportion of patients with a CD4 record actually returned to the clinic to get their CD4 test result, nor was it able to examine the reasons for the gaps in linkage to care, or to assess quality of care received.
It shows the gap in linkage to CD4 testing and the gap in linkage to viral load testing for those who were ART-eligible (the latter being a proxy for the gap in linkage to ART).
The study identified gaps in linkage to care irrespective of the HIV testing approach used.
It is thus possible that the association seen with MM here may represent linkage to estrogen related effects, either through cross-regulation effects of the two genes or via linkage to another marker in the distal parts of ESR1 that does not show linkage to those markers we have already interrogated in this study.
Indeed, many POF-associated variants in whole genome studies map within, or in linkage disequilibrium to, intronic or intergenic regions; thus, these regions likely contain causative regulatory genes or networks.
Because several study sites have very few staff involved in HIV testing or linkage to treatment in the community, penetration does not focus on staff measures, but rather focuses on the measure of penetration as the proportion of inmates who receive an HIV service such as HIV testing, prevention intervention, or linkage of HIV-infected inmates to treatment in the community.
Of the SNPs showing significant or suggestive associations with the traits, several were homologous to genes of known immune function or were in close linkage to such genes.
This can be due to these markers being linked to or in linkage disequilibrium with QTL and/or due to markers capturing pedigree relationships [ 19].
Here, 33-ϕ-OEG-lipid and 33-OEG-lipid possess the same trisaccharide and differ only in the linkage: the bulkier click-linkage to OEG in the former or the peptide linkage to OEG in the latter.
Only fragments of the original grey jungle fowl genome remain, possibly due to human selection for particular phenotypic traits such as leg colour or through linkage to genes involved in resistance to disease.
