Sentence examples for or essentiality from inspiring English sources

In comparison, dropping any one of the protein protein interactions, expression levels, or essentiality from the ANCOVA neither changed the sign nor abolished the significance of the client/nonclient term (see supplementary table 13, Supplementary Material online).

We further identified eleven (11) properties (see Table  1 for a full listing), encapsulating aspects of expression, differential expression, and network topology that provide some insight into both the role and relative importance, or essentiality, of these transcription factors in the study system.

Although metabolic labelling studies in the parasite have confirmed that multiple proteins are N-myristoylated [ 16], T. cruzi NMT has not been characterized biochemically or assessed for essentiality or druggability.

How does the number of HSRs contribute to gene functions or gene essentiality?

Results varied for other demographic and lifestyle groups, but were attenuated after adjustment, and only supplement use remained a positive predictor of belief in essentiality (adjusted OR for believing DS to be essential: 11.37 (6.35, 20.39); p < 0.001) (Table  3).

The relationship between mRNA decline and growth rate decline reflects the degree of essentiality, or stringency, of an essential gene, which is here defined by the minimum transcript level for a 50% reduction in growth rate (MTL50).

We next sought to validate iSR215 using available data on gene or gene product essentiality in T. cruzi or related species (see table 4) [ 37- 51].

For example, GES and GSL inconsistencies refer to cases where the in silico deletion of a gene pair is not lethal (i.e., Growth) but in vivo they are lethal due to gene essentiality or synthetic lethality (i.e., ESsential or Synthetic Lethal).

The generated tree does not include any splitter node using 'absolute protein abundance' or 'co-essentiality' attribute which contains many missing entries.

However, nothing is yet known about RPS4Y2 essentiality, or about its functionality, expression pattern in non-human primates, or the mechanisms associated with its survival.

Table 2 summarizes the available data on trans-translation essentiality or dispensability in several bacteria with their genome size, the number of rRNA operons and the duplication time.