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The optional substitution of a second 2-year rodent carcinogenicity study with an alternative study such as an in vivo transgenic carcinogenicity study is part of the International Conference on Harmonization guidance S1B: Testing for Carcinogenicity of Pharmaceuticals.
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We've included substitutions and optional ingredients in the book so you don't end up doing the same".
Korsgaard's argument appears to involve the sleight-of-hand substitution of an ambitious and optional notion of action for a minimal and more plausibly nonoptional one.
Patella replacement may be optional.
Thus, contrary to what Suzukamo and collaborators did, in our study no substitution was performed between the regular items with high missing rates and the corresponding optional ones with low missing rates within selected subscales [ 13].
Sideburns optional.
Eat (optional).
herbs optional.
(Anchovies optional).
Pompoms optional.
Pitch optional.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com