And Dynda Thomas, a lawyer specializing in conflict-mineral issues, believes that as NGOs issue their own public simplifications and ratings of company filings, they'll drive compliance beyond legal requirements, making the optional labels attractive.
And Dynda Thomas, a lawyer specializing in conflict-mineral issues, believes that as NGOs issue their own public simplifications and ratings of company fi lings, they'll drive compliance beyond legal requirements, making the optional labels attractive.
After central radiological confirmation of tumor progression, an optional open-label option is offered to eligible patients.
The optional open-label extension phase which follows the n-of-1 trial will be a further 6 months.
35 The study consists of a small series of n-of-1 trials followed by an optional open-label extension phase.
A4. Isolation of granulocytes (optional) Although labelling of mixed leucocytes (from step A3) is recommended, purified granulocytes can be used instead.
55 A second study enrolled 154 patients with advanced illness and opioid-induced constipation in a double-blind, randomized placebo-controlled trial, with an optional open-label phase (up to 4 months) in hospice and palliative care centers.
This study also incorporated an optional open-label extension study in which BSC patients experiencing PD in the pivotal phase III study could cross over to receive panitumumab monotherapy [ 40].
27 28 We aim to conduct a series of n-of-1 trials to obtain scientifically robust ('level 1') evidence 29 of benefits and harms of add-on treatment with ephedrine for autoimmune MG, followed by an optional open-label extension phase for patients who decide to continue treatment with ephedrine.
Forms labeled "optional" in the SF-424 (R&R) package may still be required by NIH for certain programs; "optional" doesn't always mean "optional".
