For Europe, the Regulation (EC) no 1394/2007 of the European Parliament and of the Council of 13 November 2007 on Advanced Therapy Medicinal Products (ATMPs), which is an optional classification procedure, and amending Directive 2001/83/EC and Regulation (EC) No 726/2004 is available on http://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX 32007R1394&from=EN.
The energy being transmitted and exchanged between these different energy system components is represented by the class EnergyFlow, which holds a mandatory attribute for the energyAmount (arbitrary time series of energy values) and an optional classification energyCarrier for the energy carrier (Fig. 8).
The classification includes more than 14,000 different codes allowing expansion to over 16,000 by using optional sub-classifications.
With these refinements, VPI was carried forward into the seventh edition without change, and the IASLC proposed an optional more detailed classification of pleural invasion, adapting the P category developed by the Japan Lung Cancer Society to create a PL classification [39,40].
The recent efforts led to a shared and effective framework that includes an initial facial detection, a subsequent description of facial traits, a data reduction step (optional), and a final classification step.
The proposed method consists of four major steps: (1) data pre-processing, (2) initial allocation through spatially constrained cluster analysis, (3) spatial aggregation and peripheral re-allocation of individuals, and (4) an optional hierarchical or non-hierarchical classification to summarize individual patches in few classes.
The jobs classification as mandatory or optional is based on the m i and k i values of each task.
The thresholds Th 01 and Th3 change their values autonomously for different intercepted signals with different SNRs while Th 02 and Th2 are optional empirical thresholds which can improve classification performance according to noise level.
Optional output files integrate species-level results with RDP classification results and summarize read counts according to best reference sequence hit.
Overall, the basis of the above classifications was based on clinical, imaging, routine and optional tests.
