Exact(1)
The statistical evaluation of HoxPred predictions was performed on 800 public sequences (89 Hox and 711 non-Hox), with the programs compare-classes (option matrix file) and contigency-stats from the Regulatory Sequence Analysis Tools (RSAT) [ 60]/Network Analysis Tools (NeAT) [ 61], available at http://rsat.ulb.ac.be/rsat/.ulb.ac.be/rsat/
Similar(59)
Specifically, information is typically provided in a preorganized manner, for instance, in a cues-by-options matrix (for an example, see Fig. 1 in Bröder, Glöckner, Betsch, Link, & Ettlin, 2013).
In research on multiattribute decisions, information is typically preorganized in a well-structured manner (e.g., in attributes-by-options matrices).
The default option, x4r5 matrix, was used for the prediction.
Conserved candidate transcription factor binding sites were identified using multiTF [ 63, 64] from the Mulan website, selecting the TRANSFAC professional V10.2 TFBS database for vertebrates, and selecting the "optimised for function" option for matrix similarity.
For example, per programme option, the matrix may detail the number of life-years averted, among which population groups these occur, the expected costs, and required health system capacity―this allows a quantification of the trade-offs.
The Phylip program package (7 ) was used to analyze the E protein gene sequence data: 500 bootstrap replicates (Phylip's SeqBoot Program) were fed to the Dnadist program (with Kimura's 2-parameter option), distance matrixes were analyzed with the Fitch program (which used the Fitch-Margoliash algorithm), and the bootstrap support values for the tree were calculated with the Consense program.
The vertebrate binding matrices and the only high quality matrix option were used in the profile selection, and the cut-offs for core and matrix similarity were set to 0.9999 and 0.7 respectively without any change in the other options.
Local LD analysis on SBI-06 used the full matrix option in TASSEL.
Similarity matrices were calculated using the similarity matrix option in the neighbour joining field of the arb software package.
Protein distance for each pair of orthologs was calculated using Protdist in Phylip 3.69 (33) with the Dayhoff PAM matrix option.
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