This observation, together with the conserved stromal architecture within the replacement-type metastases, strengthens the blood vessel co-option hypothesis.
If the co-option hypothesis holds, these data might help to reveal the progression of this co-option event relative to the cnidarian-bilaterian divergence as well a better understanding of the molecular mechanisms underlying bilaterian complexity and diversity.
The analytical process relies heavily on mental simulation for assessing the options, hypotheses, actions and alternative plans under consideration [ 14].
He has an alternative hypothesis.
The second contribution is identified with the assessment of real options when the suspicions for monetary option valuing hypothesis no more hold.
Supporting the latter option, the hypothesis of metabolic channeling proposes that reaction products in a metabolic pathway move from one active site to another within tightly associated multi-enzyme complexes.
Immunotherapy as a medical research field continues to grow at an exciting pace, with new options and hypothesis being introduced as cancer biology becomes better understood.
The implementation of clade-specific rate estimation further extends the range of options for hypothesis testing, and its application on the radiation of Lupinus showed that it can be used to identify differential rates of diversification between clades.
These options of hypothesis-driven research include: prospective studies, participation in a multicenter clinical trials, and assessment of advances in technology, contribution to or identification of the evidence base for clinical practice, cost-effectiveness and outcomes analysis.
Stochastic simulation remains perhaps the only viable option to test hypotheses concerning the impact of selection methods on long-term gain [ 7].
