Sentence examples for optimum gene expression from inspiring English sources

Optimum gene expression can be understood as the maximum possible ratio between the benefit due to expression of the gene at a determined level and the costs of its production [ 3].

Optimum gene expression requires a balanced contribution of the diverse processes that control this process, as a gene that is transcribed at high rates should also be efficiently translated [ 4].

The rates of gene expression are mainly determined by the DNA sequences that modulate transcription and translation processes [ 1], and the selection for efficient ribosome usage seems to be a major force that shapes the evolution of gene sequences towards optimum gene expression [ 2].

The success of gene therapy relies on the efficient delivery of the genetic material to target cells, achieving optimum long-term gene expression.

Hence, several aspects of the artificial transcription factors should be simultaneously evaluated to ensure the optimum level of gene expression from a given target site in a given cell type.

It is argued that the optimum level of gene expression, and therefore the need for increased translational accuracy and/or efficiency, may vary widely from gene to gene (Hershberg and Petrov 2008).

One possible explanation is sexual antagonism, in which there is conflict between the sexes regarding the optimum level of gene expression (Ellegren and Parsch 2007; Parsch and Ellegren 2013).

Tet was used in the range of 0.5 2  μg ml−1, since these are recommended optimum concentrations for inducible gene expression by the Tet-On system.

Lysis of mononuclear cells, followed by lysate homogenization and RNA extraction represents the optimum method for robust gene expression data and is thus recommended for obtaining robust classification results in microarray studies in acute leukemias.

Understanding the distinctive elements of each system is essential for the development of strategies for the improvement of cellulase production, either by providing the optimum environment (fermentation conditions) or increasing gene expression in these microorganisms by genetic engineering.

Although the immunohistochemical staining profile can be a useful surrogate for gene expression analysis, the optimum immunohistochemical profile of the basal-like subtype remains unclear.