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This is less still than the 2-3 log10 units reduction (Amoah et al. 2007b) which are possible by further optimizing the concentration and exposure time.
In our study, we primarily assessed a rational approach for designing and formulating ideal long-circulating nanoparticles by optimizing the concentration of chitosan (CS) and polyethylene glycol (PEG).
After conducting a series of initial enzyme stabilization experiments, combinatorial additives were selected to construct an appropriate Response Surface Model for optimizing the concentration.
The results suggest that different strains might have different response to metal ions the in medium and using a thorough screening procedure is important before optimizing the concentration of metal ions.
The efficiency of Dye-Sensitized Solar Cells (DSSC) can be significantly enhanced by optimizing the concentration of surface trap states and by tailoring the band gap energy in the semiconductor oxides used as photoanodes.
Meanwhile, we improved the technology by optimizing the concentration of Cas9 and sgRNAs and designing two adjacent sgRNAs targeting one exon for each gene, which greatly increased the targeting efficiency and bi-allelic mutations.
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Optimization of the growth medium was carried out using response surface methodology, aiming at optimizing the concentrations of the key components.
The 24 full factorial central composite design of response surface methodology was applied for optimizing the concentrations of the significant variables and to delineate their interactions.
The coercivity (Hc) was found to decrease to 6 Oe while the saturated magnetic flux density was maintained higher than 1.8 T by optimizing the concentrations of tartaric acid and citric acid in the electroless plating solution.
Despite the increased sensitivity gained by optimizing the concentrations of all 3 antibodies, the improved signal was still quite low when compared to previously reported values [ 23].
Optimizing the concentrations of ASCs, mode of delivery and the time of application need to be extensively investigated in order to use this technology in DO and CSDs.
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