Sentence examples for optimizing interaction from inspiring English sources
Training adolescents in the correct use of the online information sources is a key element in optimizing interaction with the web [ 23].
Herein, we have revisited the "optimizing interaction" hypothesis.
Actually, the authors referred to such a state as an "optimizing interaction".
Previous works using cytochrome c oxidase (COX) as a model enzyme have led to the so-called "optimizing interaction" hypothesis.
They generated a model in which mitochondrial interacting surfaces were fast evolving with respect to non-interacting parts, with the aim of exploring new possibilities of optimizing interactions; the nuclear counterparts are slow evolving (with respect to the rest of the protein) in order to "respond" to mitochondrial novelties.
In this case a set of 3D conformations for the best 2D hits is generated and analogs optimally fitting the binding pocket are identified by overlap with the query ligand and by optimizing interactions with the protein.
Our design principle is different from the conventional approach, in that instead of optimizing interactions within the target structure, we design the global shape of the protein folding funnel.
Thus, the lack of binding to the glycan array reflects an alternative structural mechanism of optimizing interactions with sugars, in this case with minimal local selectivity so that spatial distribution becomes the dominant factor in determining specificity.
Mallam et al. propose that present-day helicases have diversified from enzymes that had broad specificity for RNA and DNA, by optimizing interactions that favor the binding of particular nucleotides and nucleic acids.
An interface named MEPUC (Motorized Exact Positioning Unit for C-Arm) was designed to optimize interaction between surgeon and fluoroscope.
While the main chain of these residues are at a similar position in both bH1 structures as in the Herceptin structures, their side chains appear to undergo various extents of adjustments in order to optimize interaction with the two antigens (Figure 1, Figure S1).
