Sentence examples for optimizing alignment from inspiring English sources

When evaluated using the challenging Maximum Unbiased Validation dataset, shape constraints were able to extract significantly enriched subsets of compounds for the majority of targets, and FOMS matched or exceeded the performance of both VAMS and an optimizing alignment method of shape similarity search.

Reads of BAC pool rP were aligned using Mosaik to GenomeZipper sequence dataset with the aim to optimize alignment parameters.

In addition, we used the local alignment configuration of Bowtie2, which allows reads' end "trimming" to optimize alignment.

In order to optimize alignment parameters or measure the quality of alignments, a cost function was used which does not rely on any reference or ideal alignments.

We optimized alignment parameters (below), including the number of allowed mismatches (-v) and the number of reported mappings (-m or -a).

Unlike other multi-genome comparative tools that display columns of aligning bases with gaps to optimize alignments, EvoPrinter displays, in a single uninterrupted view, DNA sequences that are either conserved, unique or uniquely shared, including single nucleotide polymorphisms (SNPs), as they exist in the genome or MGE of interest.

The model can optimize alignments in mountainous terrain or regions with very complex geography.

Alignment is a computationally intensive process, and many computer programs (e.g., BWA aligner [ Li and Durbin, 2009]) have been devised that implement and optimize alignments according to various measures of similarity.

In contrast to most comparative multi-sequence alignment tools (reviewed by [ 7]), which display columns of sequences that contain gaps to optimize alignments, the species-centric EvoPrint is a single uninterrupted sequence and thus displays more bases in a single view than is possible with conventional alignments.

Two strategies were implemented to align these orthologous sequences using the global alignment algorithm – mlagan: 1) optimizing the alignment parameters and 2) applying a post-alignment filter.

Furthermore, suboptimal alignment behaviour for groups of novel candidate sequences can be easily corrected by manually optimizing the alignment of one of these sequences and adding it to the reference MSA.