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The best transitions per peptide were optimized using the Peptide Optimizer software tool.
Skyfire is known as the maker of Rocket Optimizer software, which allows mobile operators to leverage cloud computing and optimize video and multimedia on cell towers, including 3G and 4G LTE networks.
The optimizer software would then comb advertising price and viewership data to figure out the top-rated time slots among those on the Obama persuadable list — which could vary from market to market — and then rank them based on which produced the highest concentration of the Obama swing voters at the best rates.
The mass spectrometric parameters were optimised using the Masshunter optimizer software (version B.03.01).
Ion transitions for each analyte were optimized by flow injection analysis of individual compounds (0.1 μg/mL in methanol) using the Agilent MassHunter Optimizer software.
Precursor and product ion selection as well as the optimization of collision energies were performed with flow injection of single analyte solutions using the MassHunter Optimizer software.
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The model is formulated with the YALMIP tool in MATLAB and calculated with the optimization software Gurobi Optimizer.
A commercial optimization software, MINOS [B.A. Murtagh, M.A. Saunders, MINOS 5.4 User's Guide, Technical Report SOL 83-20R, Stanford University, Stanford, 1987, Revised February 1995], was used as the NLP optimizer.
A list of all possible b- and y-ion series for 2+ and 3+ precursor ion charge spanning a range of m/z from 200 to 1100 was generated using the Agilent MassHunter Optimizer For Peptides Software (Version B.05.00, Agilent).
Moreover optimization was done using response optimizer part of Minitab software and the values of target and allowable minimum responses were defined for the software and finally it calculated the maximum achievable values for both of the responses and also corresponding coded values of mixture components.
In the software response optimizer tool determined the optimal value for maximum antimicrobial activity.
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