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Based on this new definition of error, an optimization model is established to get the global optimized tool axis trajectory surface.
Using this framework optimized tool paths can be generated that compensate for the inaccuracy inducing behavior.
Finally, an optimized tool prototype has been manufactured and tested in order to verify the design solutions under service conditions.
Chromatographic profiles generated using this optimized tool are shown to overlay with comparable profiles from the conventional bench-scale and clinical manufacturing scale.
Various methods can be employed, focusing on the cutting edge strengthening by its rounding or by more complicated geometries including chamfer and optimized tool wedge radius and angles.
Several modified tools were tested by simulation and optimized tool shapes from the point of view of minimum number of operations and optimum thickness changes of the sheet at each stage of metal forming were found.
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The reshaping method, using optimized tools enabled to increase the strength of the joints by 32%.
To enable fast and reliable hit identification, we have designed an automated refinement pipeline that will inspire the development of optimized tools facilitating the successful application of fragment-based methods.
Facebook today is launching optimized tools to increase the speed at which deep-learning projects that use Torch run.
Evaluation of immune and genetic biomarker profiles will allow identification of pathogenic versus (BCG-induced) protective host biomarkers and could lead to effective prophylactic interventions for leprosy using optimized tools for identification of individuals who are most at risk of developing disease.
Here we report optimized tools and techniques for expanded application of the CRISPR/Cas9 system in Drosophila through homology-directed repair (HDR) with double-stranded DNA (dsDNA) donor templates that facilitate complex genome engineering through the precise incorporation of large DNA sequences, including screenable markers.
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CEO of Professional Science Editing for Scientists @ prosciediting.com