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Even though this process is highly optimized there is still interest to improve the productivity, the robustness of the strains and the product yield (van Maris et al. [2006]; Hahn-Hagerdal et al. [2007]).
While branch length estimates clearly should be optimized, there is also a real need for more accurate and multiple calibrations to reduce the uncertainty of rate estimates [ 29].
When this function is not optimized, there is an increased risk of model overfitting, where stochastic noise in training data gets incorporated and results in poor classifiers.
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The giveaway clue to this would be that however frequently we re-optimize, there would still be a similar proportion who would seem to need a change in setting.-wrap> In a busy clinical department, it may seem an unnecessary multiplication of work to make more than one measurement at each setting.
It seems unlikely that once the best immunogen has been found for a particular pathogen, and the immunogenicity of the vaccine formulation using that immunogen optimized, that there would be multiple other immunogens that would give similar protection.
As a community we need to start making our data available, not just for the purposes of the review process but in order to make the raw material accessible for the next generation of metabolomic software and bioinformatics analysis tools, which again can only be developed and optimized if there are data to work with.
For detection of a target MS reference pattern, there is typically no fixed set over which to optimize but there remains the concept of the significance of P(M) associated with its uniqueness.
Mr. Sacconaghi thinks Apple will sustain higher market share in tablets than in smartphones in part because it has been more aggressive in courting more price sensitive consumers with the iPad mini, the iPad has better global distribution than the iPhone and there are more apps optimized for the iPad than there are for competing tablets.
Answering his own question, he explained that you can do almost anything, because phones have keyboards that are optimized for English, and there are a diverse array of English-language fonts to display on most Web sites.
As the in-network taxonomy is optimized for automatic use, there is no need to include a human-readable service NAME.
First, all splits of the starting tree are optimized by NNI until there is no further improvement.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com