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This key mutation (i) removed a charged side chain that forms a buried salt bridge in the disulfide-containing wild-type protein, (ii) optimized the local packing with the residues that replace the C46 C53 disulfide and (iii) improved the domain interactions.
Consequently, using the Bayesian likelihood optimized the local Bayes factor but gave a worse global Bayes factor than the maximum likelihood approach, which also has less expensive function evaluations.
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The proposed algorithm optimizes the local energy consumption, balance the intra-cluster energy consumption.
Then, cluster processors could operate a distributed algorithm to merge and optimize the local estimates, such as described in [31].
These models optimize the local value of the model coefficients based on the dynamics of the resolved scales.
In [2], the maximum achievable throughput is obtained by optimizing the local spectrum sensing time, subject to a certain level of spectrum owner protection.
To calibrate the transition model for wind turbine applications, a long process of optimizing the local correlation variables was carried out.
The results suggest a means of optimizing the local displacements, strains and stresses by controlling the material properties of the half-space boundary.
Rather than work against the biology of bone healing, it helps optimize the local milieu and maximize the bone healing potential.
In binary tree topology analysis, we find that it is possible to optimize the local sensor network energy efficiency by making a trade-off between parameters M and β.
A linear mathematical model is presented, that optimizes the local bioenergy production and distribution system and considers various parameters such as biomass availability, the number of heat customers, or heat loss in the system.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com