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However, to the best of our knowledge, the only pairwise GPU implementation with optimized space complexity tested on the chromosome level is CUDAlign (Sandes and Melo, 2013), but it writes large amount of data to hard disk, uses a single card, and it is not publicly available.
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However, method and justification in determining an optimized spacing are rarely reported in literature.
Porosity sensitivity is an important index for determining the spacing of the neutron porosity tool, and optimized spacing can improve formation porosity resolution.
Interestingly, hydrogel printed with computationally optimized spacing created anisotropically aligned vasculature exclusively when the printed gel pattern was placed parallel to pre-existing blood vessels.
It also predicted significant variable via its "better to best" optimized spaces (independent level) and would be considered as novel statistically advanced oral drug delivery vehicle for anti-hypertensive agents.
Importantly, the optimized search space systematically yields better results than the default method not only for experimental pockets, but also for those predicted from protein structures.
The numerical results show that building parking lots at proper locations with an optimized parking space capacity could be useful in terms of allowing more intermodal transfers, reduce individual's travel time, and improve the special event visitors' accessibility.
"We really need to replace those spacecraft and their instruments that monitor CMEs and, if possible, upgrade the instruments so they are optimized for space weather monitoring – essentially to pull out the most critical data and get it back to Earth as soon as possible," he said.
We obtained a similar size of optimized regulatory space using 5'UTR median length published in [ 20].
This distance plus two times the median 5'UTR length (68 bp [ 19]) coincides perfectly with the first peak of the old divergent regions (those that are conserved in other yeast species; Figure 4), supporting our interpretation that the peak indeed represents the optimized regulatory space.
This means that despite being in a laboratory setting where many conditions are optimized (food, space, etc)., these populations were probably undergoing selection and not genetic drift (Fisher's combined probability, χ72 = 417, p < 0.0001) since the generations are out of Hardy-Weinberg equilibrium (Fisher's combined probability, χ72 = 492, p < 0.0001) and there was no assortative mating.
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