When an effect is detected, the compound is modified in different ways to optimize its activity and specificity.
Links analysis between Organizational Citizenship Behavior and virtual enterprise may mark out new action directions in order to optimize its activity.
Available data support the use of higher doses of daptomycin (8 10 mg/kg/day) in combination with a second drug (usually rifampin) in order to optimize its activity and avoid the emergence of resistance [ 29].
Even if the intein or intron has optimized its splicing activity, the insertion sequence still bears with it the burden of replicating, transcribing and in the case of inteins also translating, hundreds of superfluous nucleotides.
The PTR is likely the most important data for characterizing a hydrocarbon reservoir, forecasting its future productive performance, designing the appropriate stimulation scenario, and optimizing its management activity.
We investigated the incorporation of gemcitabine into a colloidal carrier based on the biodegradable and biocompatible poly d,l-lactide-co-glycolide) (PLGA) to optimize its anticancer activity.
Thus, the plant has been studied to provide scientific validation to its traditional usage and optimize its antimicrobial activity, both classically and statistically, using different extraction strategies and other physicochemical parameters.
If using higher than standard AMK doses is mandatory to optimize its antibacterial activity, the main concern is related to the potential development of renal damage.
In this study, we have developed pH-responsive microgels for the delivery of doxorubicin (DOX) in order to optimize its anti-tumor activity while minimizing its systemic toxicity.
To demonstrate the utility of this approach more generally for optimized enzyme immobilization, two 20-mer peptides, YHNNPGFRVMQQNKLHHGSC (referred to as YHNN) and QYHHFMNLKRQGRAQAYGSC (referred to as QYHH) were selected from a microarray of 10,000 peptides based on their ability to bind β-galactosidase (β-gal) and optimize its surface-immobilized activity (Table S1 in File S1).
