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"We evaluate the commercial potential of compounds to be optimized into drug candidates.
And the old program was optimized into a new framework, so promoted extendibility.
The original lead identified from high throughput screening was optimized into an efficient series via computer-aided structure-based drug design.
The labor that follows in the hand-off of wireframes and specs for the engineering team would be entirely optimized into implementation engines that produce flawless and exact UI layout and behavior.
However, in order to have the maximum entrainment ratio and consequently reduce energy consumption, integration of MED TVC with MED desalination must be optimized into the position of thermo-compressor suction.
Results shows that electrical fields of low energy levels and thermal effects can be combined and optimized into a single step treatment on extraction of anthocyanins and phenolic compounds from vegetable tissues providing high recovery yields with a reduced treatment time, less energy consumption and with no utilization of organic solvents (green extraction).
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Furthermore, we report that truncated variants of R1 are able to recognize mIgM-positive human B lymphoma BJAB cells at physiological temperature, demonstrating that LIGS-generated aptamers could be re-optimized into higher affinity variants.
pVpr-IN-ECFP was constructed by cloning Vpr (PCR amplified from pNL4.3) in frame with the codon optimized IN [42] into the pECFP-N1 vector (Clontech Laboratories, Inc., Saint-Germain-en-Laye, France) In addition an HIV-1 protease cleavage site (IRKVL), flanked at both C- and N- terminus by a flexible linker (KRIQST), was introduced between Vpr and IN.
With CCD, these factors can be systematically optimized taken into account of their interaction effects.
Thus, in every case, the annealing process should be optimized, taking into account properties of the dielectric matrix.
Regeneration strategies should be studied and optimized taking into account whether the reforming reactor will be used for mobile or stationary applications.
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