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To establish optimized guidelines for reproducibly linking genomic features (such as gene expression) to outcome using penalized regression (Fig. 1), we compared the LASSO, Ridge regression and Elastic Net with three strategies for 2D tuning of its penalty parameters.
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Patients are randomized to 50 mg acarbose tid or matching placebo in a 1 1 fashion on top of optimized guideline based CV care and at least 3 months out from a prior MI.
Some new rules, e.g. optimized launch power, have been found and the optimized design guidelines for short and long distance DTSS are presented.
Splice junction-specific primers were designed using Primer 3 (v 4.0) available in [ 82] and were optimized following guidelines for RT-qPCR experiments (amplification efficiency and melting curves) [ 83].
The result also provides optimized design guideline for operating SOI JLFinFET under RF range.
We developed a clinical sequencing nomenclature (CSN), a fixed variant annotation consistent with the principles of the Human Genome Variation Society HGVSS) guidelines, optimized for automated variant annotation of NGS data.
Based on these results, we provide an optimized set of guidelines for the application of penalized regression for reproducible class comparison and prediction with genomic data.
F Group was formed by patients in whom TFC was measured by thoracic bioimpedance, in order to guide intravascular volume optimization; C Group patients were optimized following "Surviving Sepsis Campaign Guidelines", recording mortality at ICU discharge and at 28 days, mechanical ventilation length and ICU length of stay.
Actual norms and guidelines are optimized in regard to economic advisements [24].
The results can be used in ergonomic guidelines to optimized information presentation on small screens.
Thus the paper help to formulate design guidelines for optimized performance of gas cooler at different ambient temperatures.
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